The unusual condition known as peripheral giant cell granuloma (PGCG) affects the gums or alveolar region. Although the cause is unknown, this lesion has been described as a response to long-term local traumas, such as trauma, ill-fitting dentures and restorations, and sub- or supragingival dental biofilm. This is a case of a 37-year-old individual complaining of swelling in the posterior mandible.
Chaparro-Avendaño AV, Berini-Aytés L, Gay-Escoda C. Peripheral giant cell granuloma. A report of five cases and review of the literature. Med Oral Patol Oral Cir Bucal 2005;10(1):53–57, 48–52.
Lester SR, Cordell KG, Rosebush MS, et al. Peripheral giant cell granulomas: a series of 279 cases. Oral Surg Oral Med Oral Pathol Oral Radiol 2014;118(4):475–482. DOI: 10.1016/j.oooo.2014.06.004
Eversole LR, Rovin S. Reactive lesions of the gingiva. J Oral Pathol 1972;1:30–38. DOI: 10.1111/j.1600-0714.1972.tb02120.x
Motamedi MH, Eshghyar N, Jafari SM, et al. Peripheral and central giant cell granulomas of the jaws: a demographic study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:e39–e43. DOI: 10.1016/j.tripleo.2006.12.022
Shafer WG, Hine MK, Levy BM. Textbook of Oral Pathology, 4th edition. Philadelphia, PA: WB Saunders; 1983. pp. 144–146.
Carvalho YR, Loyola AM, Gomez RS, et al. Peripheral giant cell granuloma. An immunohistochemical and ultrastructural study. Oral Dis 1995;1:20–25. DOI: 10.1111/j.1601-0825.1995.tb00152.x
Mannem S, Chava VK. Management of an unusual peripheral giant cell granuloma: a diagnostic dilemma. Contemp Clin Dent 2012;3(1):93–96. DOI: 10.4103/0976-237X.94556
Grand E, Burgener E, Samson J, et al. Post-traumatic development of a peripheral giant cell granuloma in a child. Dent Traumatol 2008;24(1):124–126. DOI: 10.1111/j.1600-9657.2006.00504.x
Patil KP, Kalele KP, Kanakdande VD. Peripheral giant cell granuloma: a comprehensive review of an ambiguous lesion. J Int Clin Dent Res Org 2014;6:118. DOI: 10.4103/2231-0754.143501
Adlakha VK, Chandna P, Rehani U, et al. Peripheral giant cell granuloma. J Indian Soc Pedod Prev Dent 2010;28(4):293–296. DOI: 10.4103/0970-4388.76161
Volpato LE, Leite CA, Anhesini BH, et al. Peripheral giant cell granuloma in a child associated with eruption and traumatic habit with control of four years. Case Rep Dent 2016;2016:6725913. DOI: 10.1155/2016/6725913
