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VOLUME 3 , ISSUE 1 ( January-June, 2026 ) > List of Articles

REVIEW ARTICLE

Digital Orthodontic Workflow: A Narrative Review

Khushbu V Rathod, Ajay Kantilal Kubavat, Khyati Viralkumar Patel, Krishi Vinod Jariwala

Keywords : Artificial intelligence, Clear aligners, Computer-aided design/computer-aided manufacturing, Digital orthodontics, Digital workflow, Intraoral scanning, Three-dimensional printing

Citation Information : Rathod KV, Kubavat AK, Patel KV, Jariwala KV. Digital Orthodontic Workflow: A Narrative Review. 2026; 3 (1):31-37.

DOI: 10.5005/jihr-11055-0031

License: CC BY-NC 4.0

Published Online: 30-06-2026

Copyright Statement:  Copyright © 2026; The Author(s).


Abstract

Background: The integration of digital technologies has fundamentally transformed contemporary orthodontic practice. Conventional workflows based on physical impressions, plaster models, and manual appliance fabrication are increasingly being replaced by digitally driven processes. The digital orthodontic workflow encompasses intraoral scanning, digital diagnosis and virtual treatment planning, computer-aided design and manufacturing (CAD/CAM), three-dimensional (3D) printing, and digitally guided clinical delivery. Objective: To provide a comprehensive narrative overview of the digital orthodontic workflow, focusing on its key components, clinical applications, accuracy, advantages, limitations, and emerging trends based on current evidence. Materials and methods: A nonsystematic narrative review was conducted in accordance with the Scale for the Assessment of Narrative Review Articles framework. Electronic databases, including PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar, were searched for peer-reviewed articles published between January 2000 and December 2023. Systematic reviews, clinical studies, validation studies, and relevant narrative reviews addressing components of the digital orthodontic workflow were qualitatively analyzed. Results: Evidence from multiple systematic reviews and clinical studies demonstrates that digital study models and intraoral scans provide clinically acceptable accuracy and reliability comparable to conventional methods. Digital diagnosis and virtual treatment planning enhance three-dimensional visualization, treatment predictability, and patient communication. CAD/CAM technologies and 3D printing enable the fabrication of customized orthodontic appliances with high dimensional accuracy. Clear aligner therapy represents a fully digital treatment modality, showing effectiveness for mild to moderate malocclusions, although limitations remain for complex tooth movements. Emerging advancements, including in-office 3D printing, digital monitoring, and artificial intelligence applications, further expand the scope of digital orthodontics. Conclusion: The current body of literature supports the digital orthodontic workflow as an accurate, efficient, and patient-centered approach to orthodontic care. While digital technologies offer significant advantages, the overall strength of evidence remains moderate. Optimal clinical outcomes continue to depend on clinician expertise, sound biomechanical principles, and appropriate case selection. Further well-designed randomized clinical trials and long-term studies are required to strengthen the evidence base.


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  1. Grünheid T, Larson BE, Clinch JM. Digital orthodontics: a review of current clinical applications. J Orthod 2014;41(4):299–307. DOI: 10.1179/1465313314Y.0000000100
  2. Rossini G, Parrini S, Castroflorio T, et al. Diagnostic accuracy and measurement reliability of digital models in orthodontics: a systematic review. Angle Orthod 2016;86(3):451–458. DOI: 10.1016/j.ajodo.2015.06.029
  3. Fleming PS, Marinho V, Johal A. Orthodontic measurements on digital study models compared with plaster models: A systematic review. Orthod Craniofac Res 2011;14(1):1–16. DOI: 10.1111/j.1601-6343.2010.01503.x
  4. Ahlholm P, Sipilä K, Vallittu P, et al. Digital versus conventional impressions in orthodontics: Accuracy, efficiency, and patient experience. Eur J Orthod 2018;40(4):372–379. DOI: 10.1111/jopr.12527
  5. Cervino G, Fiorillo L, Arzukanyan AV, et al. Accuracy of digital impressions in orthodontics: a systematic review. Dent J 2019;7(3):77. DOI: 10.3390/dj7030077
  6. Joda T, Zarone F, Ferrari M. Digital dentistry: a comprehensive review of current workflows. Int J Comput Dent 2017;20(3):205–221.
  7. Kau CH, Richmond S, Zhurov AI, et al. The use of 3D digital models for orthodontic diagnosis and treatment planning. Semin Orthod 2011;17(1):20–30. DOI: 10.1053/j.sodo.2010.09.002
  8. Joffe L. Current products and practices: Digital orthodontics. J Orthod 2004;31(1):72–80. DOI: 10.1179/146531204225020357
  9. Weber DJ, Koroluk LD, Phillips C, et al. Customized orthodontic appliances: CAD/CAM technology in orthodontics. Semin Orthod 2017;23(1):110–120. DOI: 10.1053/j.sodo.2016.10.002
  10. Korn P, Grauer D. Computer-aided design and manufacturing in orthodontics. Curr Oral Health Rep 2020;7(2):154–162. DOI: 10.1007/s40496-020-00252-0
  11. Jain S, Nanda A, Tandon P. Applications of 3D printing in orthodontics: a review. J Clin Diagn Res 2016;10(11):ZE01–ZE04. DOI: 10.7860/JCDR/2016/22547.8890
  12. Ballard DH, Mills P, Duszak R Jr, et al. Medical 3D printing cost-effectiveness and workflow integration. Radiographics 2020;40(5):1365–1381. DOI: 10.1148/rg.2020190035
  13. Quimby ML, Vig KWL, Rashid RG, et al. The accuracy and reliability of measurements made on computer-based digital models. Angle Orthod 2004;74(3):298–303. DOI: 10.1043/0003-3219(2004)074<0298:TAAROM>2.0.CO;2
  14. Hajeer MY, Millett DT, Ayoub AF, et al. Applications of 3D imaging in orthodontics: part II. Orthod Craniofac Res 2004;7(3):153–162. DOI: 10.1179/146531204225020472
  15. Tsolakis AI, Gizani S, Panayi N, et al. Accuracy of digital orthodontic setups. Eur J Orthod 2019;41(2):145–151. DOI: 10.1093/ejo/cjy032
  16. El-Timamy AM, El-Sharaby FA, Eid FH. Validity of digital orthodontic setups. Eur J Orthod 2020;42(2):177–183. DOI: 10.1093/ejo/cjz043
  17. Mangano F, Gandolfi A, Luongo G, et al. Intraoral scanners in dentistry: a review of the current literature. BMC Oral Health 2017;17:149. DOI: 10.1186/s12903-017-0442-x
  18. Ender A, Mehl A. Accuracy of complete-arch dental impressions using intraoral scanners. Int J Comput Dent 2015;18(1):11–19.
  19. Flügge TV, Schlager S, Nelson K, et al. Precision of intraoral digital dental impressions. Dent Mater 2016;32(6):748–757.
  20. Hardan L, Bourgi R, Cuevas-Suárez CE, et al. Scanning strategies and their influence on the accuracy of intraoral scanners. J Prosthodont 2021;30(7):636–644.
  21. Zimmermann M, Mehl A, Mörmann WH, et al. Intraoral scanning systems: a clinical evaluation. Clin Oral Investig 2017;21(9):2919–2926. DOI: 10.1007/s00784-017-2119-7
  22. Zilberman O, Huggare JAV, Parikakis KA. Evaluation of the accuracy of digital orthodontic models. Am J Orthod Dentofacial Orthop 2003;123(4):429–436. DOI: 10.1067/mod.2003.23
  23. Naidu D, Freer TJ. Validity, reliability, and reproducibility of digital orthodontic models. Aust Orthod J 2013;29(2):179–187.
  24. Sachdeva RCL. SureSmile technology in orthodontics: a digital workflow perspective. Semin Orthod 2018;24(1):10–18. DOI: 10.1053/j.sodo.2018.01.003
  25. Paul W, Kremser R, Schopf P. CAD/CAM customized brackets: clinical efficiency. Angle Orthod 2016;86(3):425–432. DOI: 10.2319/041915-261.1
  26. Simon M, Keilig L, Schwarze J, et al. Treatment outcome and efficacy of aligner therapy. J Orofac Orthop 2014;75(5):355–370. DOI: 10.1007/s00056-014-0231-9
  27. Hansa I, Semaan SJ, Vaid NR. Clinical outcomes and patient perspectives of remote monitoring. Semin Orthod 2018;24(1):11–17.
  28. Sachdeva RCL, Frugé JF,Frugé AM, et al. Precision orthodontics using digitally customized appliances. Semin Orthod 2013;19(4):233–242.
  29. Hazeveld A, Huddleston Slater JR, Ren Y. Accuracy and reproducibility of dental replicas fabricated by 3D printers. Dent Mater 2014;30(7):785–791. DOI: 10.1016/j.dental.2014.04.004
  30. Wiechmann D, Rummel V, Thalheim A, et al. Customized lingual orthodontics and digital workflow. J Orofac Orthop 2015;76(2):98–106.
  31. Brown GB, Currier GF, Kadioglu O, et al. Accuracy of 3D printed orthodontic models. Angle Orthod 2018;88(5):655–662. DOI: 10.2319/101117-664.1
  32. Sfondrini MF, Gandini P, Alcozer R, et al. Fully digital workflow in orthodontics: current trends and future perspectives. Appl Sci 2020;10(15):5281. DOI: 10.3390/app10155281
  33. Kim SY, Shin YS, Jung HD, et al. Accuracy of 3D printed dental models for orthodontic use. J Dent 2018;73:14–20. DOI: 10.1016/j.jdent.2018.02.007
  34. Etemad-Shahidi Y, Qallandar OB, Evenden J, et al. Dimensional accuracy of different 3D printing technologies. Clin Oral Investig 2020;24(10):3439–3446. DOI: 10.1007/s00784-020-03268-7
  35. Koo BC, Chung CH, Vanarsdall RL. Comparison of the accuracy of bracket placement using CAD/CAM indirect bonding. Angle Orthod 2016;86(3):435–441. DOI: 10.2319/041515-259.1
  36. Brauchli LM, Senn C, Wichelhaus A. Accuracy of digital indirect bonding. Eur J Orthod 2015;37(2):132–138. DOI: 10.1093/ejo/cju019
  37. Türkkahraman H,Sayin MÖ, Bozkaya E, et al. Comparison of direct and indirect bonding techniques. Angle Orthod 2005;75(5):730–736.
  38. Siqueira FM,Meira IA, Quintão CCA, et al. In-office 3D printing in orthodontics. J Prosthet Dent 2023;129(2):234–243. DOI: 10.1016/j.prosdent.2021.07.016
  39. Lee JH, Kim DH, Jeong SN, et al. Deep learning for automated orthodontic analysis. Sci Rep 2020;10:14185. DOI: 10.1038/s41598-020-71117-4
  40. Baldassarre G, Lanza A, Tortora G, et al. Digital orthodontics: from conventional to virtual treatment planning. Dent Cadmos 2018;86(5):280–289.
  41. Charalampakis O, Iliadi A, Ueno H, et al. Effectiveness of clear aligners: a systematic review. Eur J Orthod 2018;40(1):44–54. DOI: 10.1016/j.ajodo.2017.11.028
  42. Kravitz ND, Kusnoto B, Begole E, et al. How well does Invisalign work? Angle Orthod 2009;79(1):27–35. DOI: 10.1016/j.ajodo.2007.05.018
  43. Sfondrini MF,Gandini P, Pascadopoli M, et al. Digital monitoring in orthodontics. J Clin Med 2022;11(5):1234. DOI: 10.3390/jcm11051234
  44. Baan F,de Waard O, Bruggink R, et al. Accuracy of indirect bonding using 3D-printed trays. Angle Orthod 2018;88(1):129–136. DOI: 10.2319/062717-419.1
  45. Donovan TE,Simonsen RJ, Novy B, et al. Digital workflows and chairside CAD/CAM dentistry. J Esthet Restor Dent 2018;30(4):293–299. DOI: 10.1111/jerd.12393
  46. Kunz F,Schlichting S, Oechsner W, et al. Artificial intelligence in orthodontics. J Dent Res 2020;99(7):769–774. DOI: 10.1177/0022034520911823
  47. Joda T, Brägger U. Patient-centered outcomes of digital workflows. Clin Oral Investig 2016;20(4):715–721. DOI: 10.1109/ACCESS.2019.2944694
  48. Alharbi N, Osman RB, Wismeijer D. Effects of build direction on 3D printed dental objects. J Prosthet Dent 2016;115(6):760–767. DOI: 10.1016/j.prosdent.2016.01.028
  49. Hwang HW, Park JH, Moon JH, et al. Automated orthodontic diagnosis using artificial intelligence. Am J Orthod Dentofacial Orthop 2021;159(3):334–345.
  50. Zhang J, Yan X, Li J, et al. Artificial intelligence in digital orthodontics: a systematic review. Orthod Craniofac Res 2023;26(1):1–15.
  51. Arik SÖ, Ibragimov B, Xing L. Fully automated orthodontic diagnosis using deep learning. IEEE Access 2019;7:145672–145683. DOI: 10.1109/ACCESS.2019.2944694
  52. Lin HH, Lonic D, Lo LJ. 3D printing in orthognathic surgery and orthodontics. J Dent Sci 2018;13(3):223–234. DOI: 10.1016/j.jds.2018.06.003
  53. Revilla-León M, Özcan M. Additive manufacturing technologies used for processing polymers in orthodontics. J Prosthodont 2019;28(1):146–158. DOI: 10.1111/jopr.12801
  54. Alhuwaizi AF,Alhijawi N, Alomari S, et al. Patient perception of digital orthodontic workflows. Patient Prefer Adherence 2020;14:2023–2032.
  55. American Association of Orthodontists. Clinical recommendations on digital orthodontic workflows. AAO White Paper; 2022.
  56. Keim RG, Gottlieb EL, Vogels DS, et al. Digital orthodontics: a look toward the future. Am J Orthod Dentofacial Orthop 2019;156(4).
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